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SFN functions as an HDAC inhibitor in mammalian cells, leading to increased histone acetylation and re-expression of epigenetically silenced tumor suppressor genes (117)

This detoxification process adds an extra layer of benefit beyond just lightening

doi: 10.1016/j.jtemb.2015.07.002 109 KocakMAkarsuEKorkmazHTaysiS

Lysyl oxidase requires copper as a cofactor for its catalytic activity, and copper availability is a regulatory point in extracellular matrix biology

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